The first question you need to answer is why,why do you want to set up a brewery. It may seem like a silly question but it really is the one you first need to answer.
Next will come a clearly considered business plan,what type of beer you want to produce,one or more than one,how do you expect it to be distributed,kegs,casks,bottles.
Next come sourcing a premises suitable for brewing and acceptable to revenue.
Next comes the capital cost of your brew plant plus the cost of outfitting your premises,you will need drainage,electric and plumbing. Your energy source will need to be installed,usually electric or natural gas. If kegs are your choice of distribution,you will need to calculate a ratio of kegs for every keg you distribute,some empty,some full and in stock,some already distributed to outlets,some due for return from outlets,the further you distribute the greater ratio it will be. Also for keg beer you will need bar taps and mixed gas bottles,also cellar equipement for fitting out pubs. Bottling will require a bottling plant with labelling,packaging and pasteurizing.
When all is set up you will also need to leave room for expansion,as your brewery sales grow you should be able to install extra fermentation tanks.
Next comes your launch,you will need a good line of working capital to carry you.