I couldn't say. The 6" maps mark quite a lot of breweries and distilleries, but who can say whether these were commercial or not. i would imagine that the fact they warranted marking on a map at all would lend them some significance. Likewise, Lewis' Topographical Dictionary provided clues and mentions, and I think, given the nature of the work, he would not be listing smaller household breweries. The trade directories at least differentiate, and these could possibly be used to cross-check this theory.
When you say commercial breweries, do you mean as opposed to household breweries, or what?